Presence of luteinizing hormone/human chorionic gonadotropin receptors in male breast tissues.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 15292356.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Receptors for LH/human chorionic gonadotropin (hCG) have been found in a variety of nongonadal tissues including the female breast. Using in situ hybridization and immunohistochemistry, we demonstrated the presence of LH/hCG receptor mRNA and protein in normal male breast tissue obtained at autopsy (n = 4) and archival samples of benign gynecomastia (n = 14) and male breast carcinoma (n = 5). Although the function of these receptors remains to be determined, the findings suggest the possibility that LH and hCG may play a role in the pathogenesis of male breast disorders.
Medical subject headings
- Breast
- Breast Neoplasms, Male
- Gynecomastia
- Receptors, LH