Gene targeting: attention to detail.

Vanhaesebroeck, Bart; Rohn, Jennifer L; Waterfield, Michael D · Cell · 2004

editorial · Level V

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Abstract

When it comes to silencing genes in mice, not all approaches are equal. An example published in this issue of Cell (Patrucco et al., 2004) suggests that caution should be used when validating potential drug targets by genetic disruption.

Medical subject headings