Intraventricular cytarabine in a case of idiopathic hypertrophic pachymeningitis.
case_report · Level V
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- Record sourced from PubMed, PMID 15314132.
- Also identified by PMC identifier 1739231.
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Abstract
Idiopathic hypertrophic chronic pachymeningitis (IHCP) is characterised by inflammatory fibrotic thickening of the dura mater. Long term management is controversial. A 28 year old man with craniospinal IHCP and prominent lymphocytic meningitis is reported. Cerebrospinal fluid and histological examination suggested a CD4+ T cell driven process and B cell stimulation. After surgical, tuberculostatic, and immunosuppressive treatment failed to control the progressive meningeal hypertrophy, causing severe headache and neurological disability, the disease process eventually abated with intraventricular cytarabine treatment.
Medical subject headings
- Cytarabine
- Immunosuppressive Agents
- Meningitis