The effectiveness of rhBMP-2 in replacing autograft: an integrated analysis of three human spine studies.

Burkus, J Kenneth; Heim, Stephen E; Gornet, Matthew F; Zdeblick, Thomas A · Orthopedics · 2004

meta_analysis · Level I

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Abstract

In anterior lumbar spinal fusion, patients treated with rhBMP-2 on a collagen sponge carrier had statistically superior outcomes compared to patients treated with autogenous bone graft. A collagen sponge carrier should replace autogenous bone graft for this patient population.

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