Drosophila lifespan enhancement by exogenous bacteria.

Brummel, Ted; Ching, Alisa; Seroude, Laurent; Simon, Anne F; Benzer, Seymour · Proc Natl Acad Sci U S A · 2004

basic_science · Level V

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Abstract

We researched the lifespan of Drosophila under axenic conditions compared with customary procedure. The experiments revealed that the presence of bacteria during the first week of adult life can enhance lifespan, despite unchanged food intake. Later in life, the presence of bacteria can reduce lifespan. Certain long-lived mutants react in different ways, indicating an interplay between bacteria and longevity-enhancing genes.

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