Plasma atrial natriuretic peptide (ANP) in relation to blood pressure in severe hypertension.
case_control · Level III
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Abstract
Atrial natriuretic peptide-like immunoreactivity in plasma (ANP-LI) was studied in patients with severe hypertension (n = 21) and in matched healthy control subjects. There was no correlation between ANP-LI and blood pressure, and the distribution of ANP-LI values did not differ between the two groups. These results are consistent with the assumption that an increase in ANP is not caused by elevated blood pressure, although elevated ANP-LI may be found in subgroups of hypertensive subjects with increased atrial pressures due to, for example, cardiac failure.
Medical subject headings
- Atrial Natriuretic Factor
- Hypertension