Activated platelets in transient global amnesia and TIA.

Hirabayashi, Hisayuki; Shimizu, Mie; Kohara, Saori; Shinohara, Yukito · Neurology · 2004

cross_sectional · Level IV

Where this comes from

Abstract

To assess whether platelets are activated in transient global amnesia (TGA) and TIA, blood samples were analyzed by fluorescence-activated cytoscan using antibodies specific for platelet fibrinogen receptor (PAC1) and P-selectin (CD62P). Samples from TIA contained high levels of CD62P compared with age-matched control subjects, whereas those from TGA did not. The authors suggest that activated platelets are involved in brain ischemia, whereas ischemia appears not to be associated with most TGA.

Medical subject headings