Obsessive-compulsive disorder after unilateral caudate nucleus bleeding.

Thobois, S; Jouanneau, E; Bouvard, M; Sindou, M · Acta Neurochir (Wien) · 2004

case_report · Level V

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Abstract

Obsessive compulsive disorders (OCD) may be encountered after basal ganglia lesions of various aetiologies. These lesions are usually bilateral. We report here the case of a 24 years old man who developed a pure compulsive behavior after a unilateral left-sided caudate nucleus hemorrhage due to a cavernoma. The pathophysiology of this compulsive disorder probably reflects a frontal cortex deafferentation mechanism. Behavioral, psychological and medical (serotoninergic) treatments are usually proposed but the efficacy of such therapy remains to be investigated in secondary OCD.

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