easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses.
other · Level V
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Abstract
We have generated the program easyLINKAGE that combines automated setup and performance of linkage analyses and simulation under an easy to handle graphical user interface for Microsoft Windows 2000/XP and standard UNIX systems. The program package supports two-point linkage analyses (FastLink v4.1 and SPLink v1.09), multi-point linkage analyses [GENEHUNTER v2.1, GENEHUNTER-PLUS with the emendation by Kong and Cox v1.2 (allele sharing modelling)] and the simulation package SLINK v2.65, and provides genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters. http://www.uni-wuerzburg.de/nephrologie/molecular_genetics/molecular_genetics.htm Supplementary information is available on the website.
Medical subject headings
- Chromosome Mapping
- DNA Mutational Analysis
- Models, Genetic
- Programming Languages
- Software
- User-Computer Interface