The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study.
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- Record sourced from PubMed, PMID 15356790.
- Also identified by PMC identifier 3170406.
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Abstract
Pharmacologic doses of growth hormone (GH) reduce HIV-associated fat accumulation but may worsen glucose metabolism. We investigated the effects of a low dose of GH (1 mg per day) in HIV-infected men with fat accumulation and found that such treatment reduced total fat and increased lean body mass without significant changes in glucose tolerance or insulin sensitivity. Visceral adipose tissue (VAT) levels did not change significantly for the group as a whole, although a reduction in the VAT level was seen in patients with a greater VAT level at baseline.
Medical subject headings
- Growth Hormone
- HIV Infections
- HIV-Associated Lipodystrophy Syndrome