Long-term effect of CPAP in the treatment of nocturnal stridor in multiple system atrophy.

Iranzo, A; Santamaria, J; Tolosa, E; Vilaseca, I; Valldeoriola, F; Martí, M J; Muñoz, E · Neurology · 2004

case_series · Level IV

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Abstract

The authors found that continuous positive airway pressure (CPAP) eliminated video-polysomnographic documented stridor in 13 multiple system atrophy (MSA) subjects with vocal cord abnormalities. Long-term follow-up showed high CPAP tolerance, no recurrence of stridor, no major side effects, subjective improvement in sleep quality, and that median survival time was similar to a group of 26 MSA patients without stridor. This study shows that in MSA, CPAP is an effective noninvasive long-term therapy for nocturnal stridor.

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