Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray.

CMAJ · 2004

case_report · Level V

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Abstract

Oxymetazoline is a sympathomimetic amine found in over-the-counter nasal decongestants. We report a case of chronic use of nasal oxymetazoline associated with thunderclap headache due to reversible segmental intracranial vasoconstriction.