Blood transfusions in the therapy of a case of prolidase deficiency.
case_report · Level V
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- Record sourced from PubMed, PMID 1536787.
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Abstract
A case is reported of a 15-year-old boy with prolidase deficiency and marked urinary excretion of the iminodipeptide gly-pro. Prolidase activity of erythrocytes against substrate glycyl-proline was deficient, but after blood transfusions this was increased to 15.7% of donor activity and declined to 12% and 3.4% of normal activity after 8 and 45 days, respectively. Urinary iminodipeptide levels following transfusion remained unaltered.
Medical subject headings
- Blood Component Transfusion
- Dipeptidases
- Dipeptides
- Foot Ulcer