Nucleation of calcium phosphate by surface-bound extracellular matrix.
basic_science · Level V
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Abstract
The native extracellular matrix (ECM) laid down on silicon and titanium surfaces by osteoblast-like SAOS-2 cells was exposed by selective removal of cells. This type of material surface ECM-Si, ECM-Ti was shown to promote the nucleation of calcium phosphate from a simulated body fluid (SBF). Microscopic and spectroscopic results revealed the effect was associated with a collagen fiber-free extracellular matrix.
Medical subject headings
- Calcium Phosphates
- Coated Materials, Biocompatible
- Extracellular Matrix