The C. elegans genome sequencing project: a beginning.

Sulston, J; Du, Z; Thomas, K; Wilson, R; Hillier, L; Staden, R; Halloran, N; Green, P et al. · Nature · 1992

basic_science · Level V

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Abstract

The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.

Medical subject headings