The polymerase chain reaction and cancer diagnostics.

Lyons, J · Cancer · 1992

review · Level V

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Abstract

In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-proteins.

Medical subject headings