Selection of appropriate cellular and molecular biologic diagnostic tests in the evaluation of cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 1540902.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In this article, the use of cellular and molecular markers to diagnose and stage tumors is discussed. Their role in the evaluation of tumor prognosis and tumor susceptibility also is covered. The immunologic, cytogenetic, and molecular phenotype is discussed. Traditional markers are compared with newer methodologic approaches including evaluation of oncogenes, tumor suppressor genes, and genes that predict tumor susceptibility. These discussions are presented in relation to specific tumors. Finally, statements one might use to decide which tests to perform are presented.
Medical subject headings
- Biomarkers, Tumor
- Genetic Markers
- Neoplasms