Unusual cardiovascular localization of nonamyloid immunoglobulin deposition disease causing sudden death.
case_report · Level V
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Abstract
The case of a 38-yr-old man is presented in whom sudden death was attributed to coronary ostial stenosis caused by aortic intimal deposits of an amyloid-like material. Autopsy revealed wide-spread lymphocytic lymphoma with kappa light chain restriction. Histochemistry, immunoperoxidase light microscopy, transmission electron microscopy, and immunoelectron microscopy identified the coronary ostial, and massive other cardiovascular, deposits as para-amyloid of kappa light chain origin.
Medical subject headings
- Cardiovascular System
- Death, Sudden
- Immunoglobulin kappa-Chains