The first successful parathyroid transplant from an identical twin for the cure of permanent postoperative hypoparathyroidism.

Abstract

Long-lasting hypoparathyroidism is a severe disease with poor response to unsatisfactory therapy. A successful parathyroid isograft in a patient with postoperative hypoparathyroidism from an identical twin was performed in December 1984. Function was proved by the increase of serum parathyroid hormone from undetectable to normal levels, the ability to discontinue all supportive medications, and the maintenance of normal calcium homeostasis to date. The combination of hypoparathyroidism and the availability of an identical twin will be rare, but if it occurs parathyroid isografting should be considered.