Cosegregation of Christmas disease and major affective disorder in a pedigree.
case_report · Level V
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- Record sourced from PubMed, PMID 1543989.
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Abstract
Three males with factor-IX deficiency (Christmas disease) in one pedigree all had severe affective disorder. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for major affective disorder is located on the X chromosome.
Medical subject headings
- Bipolar Disorder
- Depressive Disorder
- Genetic Linkage
- Hemophilia B
- Sex Chromosome Aberrations
- X Chromosome