Eight fundamental unsolved problems in sarcoidosis.

Eur J Intern Med · 2004

Level V

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Abstract

More than 100 years since the identification and characterization of sarcoidosis, its etiology, fundamental nature, pathogenesis, incidence, ethnic predilections, relationship to the Kveim test and prognostic determinants remain largely either unknown or unexplained, and treatment indications, absent compelling findings, remain undefined. Professor Hilbert's "Address" delineates these fundamental deficits in our knowledge and understanding.