Neuronal differentiation: TOR and insulin receptor pathways set the tempo.
review · Level V
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Abstract
Target of rapamycin (TOR) and insulin receptor pathways regulate growth in metazoans. A recent study reveals a novel role for these pathways in controlling the timing of neuronal differentiation during Drosophila development, thus allowing a tight coordination between growth and differentiation programs.
Medical subject headings
- Cell Differentiation
- Drosophila Proteins
- Nervous System
- Neurons
- Phosphatidylinositol 3-Kinases
- Receptor, Insulin