Conjunctival metastasis as initial sign of disseminated cutaneous melanoma.

Abstract

To describe a patient with conjunctival metastasis as the initial manifestation of metastasis from a cutaneous melanoma. Single interventional case report. A 48-year-old woman with a history of cutaneous axillary melanoma developed a rapidly growing conjunctival mass. Subsequent systemic evaluation disclosed asymptomatic liver metastasis. The conjunctival lesion was resected. Histopathologic evaluation of the conjunctival tumor disclosed an epithelioid cell melanoma located in the conjunctival stroma, without appreciable junctional activity, compatible with metastatic melanoma. Conjunctival metastasis from cutaneous melanoma can rarely be the initial manifestation of disseminated melanoma.