Vasculitis associated with the use of leflunomide.

Macdonald, Jeannie; Zhong, Toni; Lazarescu, Adriana; Gan, Bing Siang; Harth, Manfred · J Rheumatol · 2004

case_report · Level V

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Abstract

Vasculitis as a complication of leflunomide therapy in the treatment of rheumatoid arthritis has been reported. We describe a case of acute necrotizing vasculitis following leflunomide therapy. Characteristics of this case and 4 cases in the literature suggest that vasculitis may be a rare but serious adverse effect of leflunomide therapy.

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