Midazolam sedation reversed with flumazenil for cardioversion.

Fennelly, M E; Powell, H; Galletly, D C; Whitwam, J G · Br J Anaesth · 1992

rct · Level II

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Abstract

Midazolam was used for anaesthesia in 20 patients undergoing cardioversion; 10 received flumazenil, which caused immediate rapid reversal of anaesthesia, and these patients maintained SpO2 greater than 95%, breathing air, within 5-10 min. In contrast, patients in the placebo group were still partially sedated and required oxygen therapy for up to 2 h to maintain a normal SpO2. Arterial pressure, but not heart rate, also was greater in the flumazenil group in the recovery period.

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