Endothelial cell culture: beginnings of modern vascular biology.
basic_science · Level V
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- Record sourced from PubMed, PMID 15489946.
- Also identified by PMC identifier 522268.
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Abstract
Endothelial cells derived from human umbilical veins were first successfully cultured in vitro in 1973. Weibel-Palade bodies and the von Willebrand factor antigen were used as morphological, immunohistochemical, and functional markers to unequivocally identify the cells. These landmark studies helped initiate the growth of modern vascular biology.
Medical subject headings
- Cell Culture Techniques
- Endothelial Cells
- Endothelium, Vascular