Pharmacokinetics and pharmacodynamics of levodopa.

Montgomery, E B · Neurology · 1992

review · Level V

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Abstract

Levodopa is effective in relieving symptoms of Parkinson's disease. However, long-term complications make sustained control problematic. Most management problems are related to the pharmacokinetic and pharmacodynamic properties of levodopa. Careful titration based on pharmacologic principles may achieve optimal therapeutic effects.

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