Cellular infiltration of the vitreous in a patient with X-linked immunodeficiency with increased IgM.
case_report · Level V
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Abstract
We studied visual impairment caused by benign lymphoid infiltration of the vitreous bilaterally, as a complication of a primary immunodeficiency, X-linked immunodeficiency with increased IgM in an 8-year-old boy. Immunophenotyping of a vitreous aspirate showed a mixed cell population, including lymphocytes (T helper, suppressor-cytotoxic T cells, and B cells) and macrophages. Cultures of the vitreous were negative for bacterial or fungal pathogens. The vitreous infiltrates have been resistant to treatment with corticosteroids and cytotoxic agents.
Medical subject headings
- Agammaglobulinemia
- Hypergammaglobulinemia
- Immunoglobulin M
- Vitreous Body