Cutaneous nocardiosis complicating management of Crohn's disease with infliximab and prednisone.
case_report · Level V
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- Record sourced from PubMed, PMID 15505269.
- Also identified by PMC identifier PMC262730.
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Abstract
Infliximab is a chimeric anti-tumour necrosis factor-alpha antibody that is efficacious in treating Crohn's disease. However, its immunomodulatory properties increase susceptibility to opportunistic infections. We present a case of cutaneous Nocardia infection in a patient who was taking infliximab for Crohn's disease. The case illustrates the challenges in the diagnosis and management of this disease and serves as a reminder of the complications associated with the use of immunomodulatory agents.