Serum lipids and hippocampal volume: the link to Alzheimer's disease?
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 15505826.
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Abstract
The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High-density lipoprotein cholesterol, but not low-density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high-density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease.
Medical subject headings
- Alzheimer Disease
- Hippocampus
- Lipids