Flypaper for parasites.
editorial · Level V
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Abstract
In this issue, Kamhawi et al. (2004) describe the identification of an insect galectin as the receptor for the stage-specific Leishmania adhesin lipophosphoglycan (LPG). This interaction is critical for parasite survival in the midgut of its sand fly vector. The results open new avenues for studies of insect immunity, transmission binding vaccines, and host-parasite coevolution.
Medical subject headings
- Galectins
- Glycosphingolipids
- Insect Vectors
- Leishmania
- Psychodidae