Epithelioid sarcoma. Flow cytometric study of DNA content and regional DNA heterogeneity.

el-Naggar, A K; Garcia, G M · Cancer · 1992

case_series · Level IV

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Abstract

The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and intertumoral DNA content. Small tumor size (less than 5.0 cm) and low S-phase fraction (less than 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.

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