Anxiety and the risk of death in older men and women.

van Hout, Hein P J; Beekman, Aartjan T F; de Beurs, Edwin; Comijs, Hannie; van Marwijk, Harm; de Haan, Marten; van Tilburg, Willem; Deeg, Dorly J H · Br J Psychiatry · 2004

prospective_cohort · Level II

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Abstract

There are inconsistent reports as to whether people with anxiety disorders have a higher mortality risk. To determine whether anxiety disorders predict mortality in older men and women in the community. Longitudinal data were used from a large, community-based random sample (n=3107) of older men and women (55-85 years) in The Netherlands, with a follow-up period of 7.5 years. Anxiety disorders were assessed according to DSM-III criteria in a two-stage screening design. In men, the adjusted mortality risk was 1.78 (95% CI 1.01-3.13) in cases with diagnosed anxiety disorders at baseline. In women, no significant association was found with mortality. The study revealed a gender difference in the association between anxiety and mortality. For men, but not for women, an increased mortality risk was found for anxiety disorders.

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