Paternal origin of the de novo deleted chromosome 4 in Wolf-Hirschhorn syndrome.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 1552546.
- Also identified by PMC identifier 1015823.
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Abstract
The parental origin of the de novo deleted chromosome 4 was studied in five cases of Wolf-Hirschhorn syndrome using polymorphic probes mapping in the 4p16.3 region. In all the patients the deleted chromosome was found to be of paternal origin and these results, together with similar ones obtained by another group, make the preferential paternal origin of the de novo chromosome 4 deletion highly significant.
Medical subject headings
- Abnormalities, Multiple
- Chromosome Deletion
- Chromosomes, Human, Pair 4