High incidence of orbital malignant lymphoma in Japanese patients.

Abstract

To review 244 cases of orbital tumors to determine pathologic findings in Japanese patients. Observational case series. We studied the pathology and origin of tumors in the orbit in 244 consecutive Japanese patients with orbital tumors at our institution from 1981 through 2002 (age 0 to 90 years, mean, 48.7 years; 114 men, 130 women). The most common tumors were lymphoproliferative diseases (n = 114, 42.5%), including malignant lymphoma (n = 59, 24.1%) and reactive lymphoid hyperplasia (n = 45, 18.4%), pleomorphic adenoma (n = 21, 8.6%), and cavernous hemangioma (n = 18, 7.4%). The incidence of lymphoproliferative diseases, especially malignant lymphoma, was very high in Japanese patients.