Clostridial myonecrosis resulting from subcutaneous epinephrine suspension injection.

Hallagan, L F; Scott, J L; Horowitz, B C; Feied, C F · Ann Emerg Med · 1992

case_report · Level V

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Abstract

A 32-year-old asthmatic man developed a life-threatening Clostridium perfringens infection after subcutaneous epinephrine suspension injection. Extensive surgical debridement, including forequarter amputation, hyperbaric oxygen therapy, and appropriate antibiotics were used as life-saving measures. The patient made a fair functional recovery. We could find no previously reported cases of gas gangrene following subcutaneous injection in otherwise healthy individuals. The pathogenesis and treatment of this infection are discussed.

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