MACAT--microarray chromosome analysis tool.
other · Level V
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Abstract
By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions. We demonstrate the applicability of the approach on a publicly available data set on acute lymphocytic leukemia. The R-package MACAT can be obtained from http://www.compdiag.molgen.mpg.de/software/macat.shtml http://www.compdiag.molgen.mpg.de/software/macat.shtml.
Medical subject headings
- Algorithms
- Chromosome Mapping
- Gene Expression Profiling
- Models, Statistical
- Oligonucleotide Array Sequence Analysis
- Software