Intralesional interferon alfa-2b treatment of keratoacanthomas.
case_series · Level IV
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Abstract
Complete excision is not always easy when a keratoacanthoma is large or located in certain anatomic areas. An effective nonsurgical treatment would be desirable in such cases. This was a pilot study of the effects of intralesional interferon alfa-2b in the treatment of rapidly growing keratoacanthomas. A total of 4 large, rapidly growing keratoacanthomas, which were located on the lower lip, neck, and cheeks of the 4 different patients, were treated with intralesional interferon alfa-2b injection weekly. Serial photographs were taken to observe the course of responses. All lesions resolved completely in 5 to 7 weeks with acceptable cosmetic results. Intralesional interferon alfa-2b can be a treatment modality of these difficult lesions.
Medical subject headings
- Cheek
- Interferon-alpha
- Keratoacanthoma
- Lip Diseases
- Neck