Familial total ophthalmoplegia with iris transillumination (a neurocristopathy).

Cibis, G W; Tripathi, R C; Tripathi, B J; Seidel, F G · Am J Ophthalmol · 1992

case_report · Level V

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Abstract

A family with total (internal and external) ophthalmoplegia had associated iris transillumination. No abnormal visual-evoked response brain lateralization indicative of albinism was found. On the basis of avian chimera experiments showing iris muscles to be derived from neural crest cells, we proposed a neurocristopathic theory to explain all clinical findings in this family.

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