Pemphigus foliaceus with neutrophilic spongiosis evolving to an atypical pemphigus phenotype.
case_report · Level V
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Abstract
A 46-year-old Brazilian man, with initial pustular lesions, neutrophilic spongiosis and subcorneal cleavage evolved to an atypical pemphigus phenotype, with suprabasal acantholysis. Interestingly, his autoantibody profile, tested by immunofluorescence, immunoblotting, enzyme-linked immunosorbent assay, and immunoprecipitation revealed exclusive IgG anti-desmoglein 1 antibodies in all phases of the disease.
Medical subject headings
- Pemphigus
- Skin Diseases, Vesiculobullous