Reduction of carboxyhaemoglobin levels in the venous blood of cigarette smokers following the administration of carbogen.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 15588884.
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Abstract
Cigarette smokers have high carboxyhaemoglobin levels which can promote tumour radioresistance. Inhalation of carbogen gas shortens the half-life of carboxyhaemoglobin, increasing tumour radiosensitivity in animal models. Breathing 2.5% carbogen for 30 min results in a greater reduction in venous blood COHb levels than breathing 5% carbogen for 7 min.
Medical subject headings
- Carbon Dioxide
- Carboxyhemoglobin
- Oxygen
- Radiation-Sensitizing Agents
- Smoking