The ways of PARP.
editorial · Level V
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- Record sourced from PubMed, PMID 15607968.
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Abstract
Two papers in this issue of Cell describe two roles of poly(ADP-ribose) polymerase (PARP) in modulating chromatin structure: as a structural component replacing linker histone (Kim et al., 2004) and as a constituent of a corepressor complex poised to dismiss repression upon receipt of an activating signal (Ju et al., 2004).
Medical subject headings
- Chromatin
- Histones
- Nucleosomes
- Poly(ADP-ribose) Polymerases
- Repressor Proteins