Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient.
case_report · Level V
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Abstract
Hemorrhagic cystitis that occurs late after bone marrow transplantation (BMT) in BMT recipients is often associated with adenovirus or polyomavirus BK infections. Intravesical instillation of cidofovir in a BMT recipient with intractable hemorrhagic cystitis resulted in clinical improvement. Local cidofovir therapy for viral hemorrhagic cystitis could be an alternative to intravenous administration of cidofovir.
Medical subject headings
- Adenoviridae
- Adenovirus Infections, Human
- Antiviral Agents
- Bone Marrow Transplantation
- Cystitis
- Cytosine
- Organophosphonates