Contrast-enhanced MR angiography at 1.5 T after implantation of platinum stents: in vitro and in vivo comparison with conventional stent designs.

Abstract

The objective of our study was to evaluate the in vitro and in vivo 3D contrast-enhanced MR angiography characteristics of a new platinum-based balloon-expandable stent system and compare this system with a variety of competing metallic stents. All experiments were performed on 1.5-T scanners. In vitro experiments were performed using 10 stents implanted into a custom-built phantom. Different orientations of the stents along the magnetic field and multiple flip angles were examined. In addition, 19 patients underwent contrast-enhanced MR angiography after the implantation of 36 stents, including four patients with six platinum stents. Angiographic correlation was available for all 19 patients, and luminal patency and stent-induced artifacts were assessed quantitatively. Of the tested balloon-expandable stents, only the platinum-based stents created artifact causing luminal narrowing of 30% or less. All other balloon-expandable stents induced larger artifacts that resulted in higher degrees of narrowing. Thus, if patent, the platinum-based stents allow significant in-stent stenosis to be ruled out reliably. Selected nitinol- or tantalum-based self-expandable stents also are suitable in this regard. Of the tested devices, platinum-based stents are the only type of currently available balloon-expandable stent that creates 30% or less artifact-induced apparent stenosis and thus are suitable for MR angiography.