Ribosome biogenesis: giant steps for a giant problem.
editorial · Level V
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Abstract
In this issue of Cell, the Hall group describes how the rapamycin-sensitive TOR signaling network controls ribosomal protein (RP) gene expression via the Forkhead-like transcription factor FHL1 in budding yeast (Martin et al., 2004). These findings represent a crucial advance in our understanding of the mechanism by which TOR regulates ribosome biogenesis in response to environmental cues.
Medical subject headings
- Gene Expression Regulation, Fungal
- Nuclear Proteins
- Phosphatidylinositol 3-Kinases
- Phosphotransferases (Alcohol Group Acceptor)
- Ribosomes
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors