Physical training and fatigue, fitness, and quality of life in Guillain-Barré syndrome and CIDP.

Garssen, M P J; Bussmann, J B J; Schmitz, P I M; Zandbergen, A; Welter, T G; Merkies, I S J; Stam, H J; van Doorn, P A · Neurology · 2004

case_series · Level IV

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Abstract

Many patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) experience excessive fatigue, which may persist for years and reduce quality of life. The authors performed a 12-week study of bicycle exercise training in 20 patients with severe fatigue, 16 with relatively good recovery from GBS, and 4 with stable CIDP. Training seemed well tolerated, and self-reported fatigue scores decreased 20% (p = 0.001). Physical fitness, functional outcome, and quality of life were improved.

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