Neurofibrillary tangles in ALS and Parkinsonism-dementia complex focus in Kii, Japan.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 15623711.
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Abstract
Brains of 41 residents without neurodegenerative diseases in the high-incidence area of ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii Peninsula of Japan were neuropathologically examined. Neurofibrillary tangles (NFTs) in the hippocampal area were present in 11 of the 41 cases, but the frequency of NFT-positive cases in each age group was similar to that of the normal Japanese population and far less than that of Guamanians without ALS/PDC.
Medical subject headings
- Amyotrophic Lateral Sclerosis
- Brain
- Dementia
- Neoplasms
- Neurofibrillary Tangles
- Parkinson Disease