Peri-ictal SPECT and surgical treatment for intractable epilepsy related to schizencephaly.
case_series · Level IV
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Abstract
The authors evaluated four patients with schizencephaly who underwent subtraction ictal SPECT coregistered to MRI (SISCOM) prior to epilepsy surgery. Three patients had a SISCOM alteration that was concordant with the epileptic brain tissue. Two of these patients were rendered seizure-free and one individual experienced a significant reduction in seizures. The patient with an indeterminate SISCOM had an unfavorable outcome. SISCOM is useful in evaluating patients with schizencephaly for epilepsy surgery.
Medical subject headings
- Cerebral Cortex
- Epilepsies, Partial
- Tomography, Emission-Computed, Single-Photon