Mycobacterial brain abscess possibly due to bacille Calmette-Guérin in an immunocompromised child.

Coppes, M J; Olivieri, N F; Howes, M; Pusic, M; Gold, R; Richardson, S E · Clin Infect Dis · 1992

case_report · Level V

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Abstract

Disseminated infection with bacille Calmette-Guérin (BCG) is rare, even in immunocompromised patients who receive BCG injections as immunotherapy or immunization. When such infection occurs, it is usually in patients with decreased cellular immunity. A 6-year-old Caucasian girl who was receiving maintenance chemotherapy for acute lymphoblastic leukemia presented with symptoms of meningitis. A temporal-lobe biopsy revealed acid-fast bacilli that were identified as Mycobacterium bovis BCG. Neither the patient nor any family members had been immunized previously. Appropriate therapy resulted in a complete recovery.

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