Hearing loss and extent of labyrinthine injury in Pseudomonas otitis media.

Malaty, John; Lee, James C; Zhang, Mei; Stevens, Gary; Antonelli, Patrick J · Otolaryngol Head Neck Surg · 2005

basic_science · Level V

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Abstract

To determine if the severity of hearing loss due to semicircular canal transection (SCT) in Pseudomonas otitis media (POM) is a function of the extent of the labyrinthine injury. POM was induced bilaterally in 45 guinea pigs. After 2 to 4 days, SCT was performed in one 1 on the horizontal canal, the superior canal, or both the horizontal and the superior canals. Auditory-evoked brainstem responses were measured before and after SCT. POM was induced bilaterally in all animals. Elevation of click thresholds was found in almost all SCT ears of all 3 groups; however, there were no significant differences between groups. Comparing the SCT ear to the contralateral, control ear, mean hearing losses in the horizontal, superior, and horizontal + superior SCT groups were 23 dB, 27 dB, and 24 dB, respectively. Hearing loss does not correlate with extent of labyrinthine injury in POM in the guinea pig. B-2.

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